November 28, 2022

One of the NFL’s classic rivalries will be renewed on Sunday when the Green Bay Packers host the Dallas Cowboys. Those teams have met eight times in the playoffs, the third most of all time, and Dallas is a five-point favorite in the latest Week 10 NFL odds from Caesars Sportsbook. Elsewhere in the NFC, the Eagles will be looking to become the 21st team since the undefeated Dolphins of 1972 to start a season 9-0. Philadelphia will host Washington, with the Eagles 10.5-point favorites according to Week 10 NFL spreads. Dallas’ 6-2 against the spread record is the best in the league, while Green Bay’s 3-6 record is among the worst. Is backing the Cowboys with your Week 10 NFL picks a wise choice, or should your NFL betting strategy favor Aaron Rodgers and co.? Which teams should you target for your NFL survivor picks and NFL office pool picks? All of the week 10 NFL lines are listed below and SportsLine’s advanced computer model includes all the NFL betting advice and predictions you need to start making the best week 10 NFL picks right now.

The model, which simulates every NFL game 10,000 times, has won more than $7,000 for $100 players with top-tier NFL picks since its inception. The model kicks off Week 10 of the 2022 NFL season with an incredible 151-108 run of top-flight NFL picks that stretches back to the 2017 season.

The model has also ranked in the top 10 on NFLPickWatch in four of the last six years with straight NFL picks, beating more than 94% of CBS Sports football pick ’em players four times in that span. Whoever followed it is way up.

Now it has turned its attention to the latest Week 10 NFL odds and laid out tips for each NFL matchup. Go here to see each selection.

Top Week 10 NFL Predictions

One of the model’s strongest Week 10 NFL picks is that the Titans (-3) cover the spread at home against the Broncos nearly 60% of the time. Tennessee might just come up short in overtime against the Chiefs in Week 9, but the Titans covered for the sixth straight game. Her 6-2 against the spread record this year is the best mark in the league. Meanwhile, Denver has just three wins against the spread, which is the second fewest in the NFL.

Denver is terrible on offense and ranks 30th in points, 31st in third-down conversion percentage, and 32nd in red zone percentage. The Titans held Kansas City’s No. 1 leading scorer to just 20 points, a mark Denver has only matched twice this season. Derrick Henry has reclaimed his throne as the frenzied king of the NFL and leads the league in yards (870) and has surpassed 100 yards in five straight games. While the Broncos are strong defensively, this will also be their first game after dropping their best defensive player Bradley Chubb.

The model has won Tennessee (-3) by more than one field goal and also says Over (39) will score with teams expected to score 41 points. See which other teams you should pick here.

Top Week 10 NFL Survivor Picks

The model’s Week 10 NFL knockout pool picks say to avoid the Saints even though they’re favorites over the Steelers. New Orleans leaves a short week after Monday’s game and will visit a Steelers team leaving a bye. Recovery means more in football than in any other sport, and Pittsburgh will have an eight-day lead in that regard.

New Orleans has also lost consecutive road games to teams with a combined 5–13 record. As for Pittsburgh, their last home game was an upset win over the Buccaneers, and the team was able to win back reigning Defensive Player of the Year TJ Watt. Few players on either side of the ball influence their team more than Watt, as Pittsburgh is 52-24-2 (.684) when he’s playing compared to 1-10 (.090) when he’s not playing. Given New Orleans’ struggles away from the Superdome, the model avoids the Saints in Week 10 NFL Survivor Pool picks. See here which team you should choose.

Top Week 10 NFL Office Pool Picks

One of the strongest Week 10 NFL football pool picks from the model is the Giants beating the Texans. While Houston is set to take a mini bye after last Thursday’s game, New York is coming to a traditional bye after the ninth week. The Giants will have the remaining advantage as well as the historical advantage since they won four straight encounters against the Texans.

Houston has lost three straight games this season, and those losses average 12.3 points. It’s hard to see a path to victory for a Texas team ranked 29th in total offense and 30th in total defense. Saquon Barkley is expected to have 94 rushing yards and 34 receiving yards. It’s also predicted that New York will have multiple takeaways and multiple sacks, which will be too much for Houston’s offense to overcome. See which other teams you should pick here.

How to make NFL picks for week 10

The model has also called who wins and covers in every other game on the NFL week 10 schedule, and it also says a Super Bowl contender goes down hard. It also backs a shocking team in its NFL survivor picks. You can get every selection for every game only at SportsLine.

So what NFL predictions, NFL pool picks, and NFL survivor picks can you hit with confidence? And which Super Bowl contender goes down hard? Check out the latest NFL odds below, then visit SportsLine to see which teams are winning and cover the range, all from a proven computer model that has grossed more than $7,000 since inception and find it it out.

Week 10 NFL odds, lines, spreads

Get full NFL picks at SportsLine

Thursday 10 Nov

Falcons at Panthers (+3, 43.5)

Featured Game | Carolina Panthers vs. Atlanta Falcons

Sunday 13 Nov

Seahawks at Buccaneers (-2.5, 44.5)

Featured Game | Tampa Bay Buccaneers vs. Seattle Seahawks

Vikings at Bills (-7.5, 48)

Featured Game | Buffalo Bills vs. Minnesota Vikings

Lions in bears (-2.5, 48.5)

Featured Game | Chicago Bears vs. Detroit Lions

Jaguars at Chiefs (-9.6, 50)

Featured Game | Kansas City Chiefs vs. Jacksonville Jaguars

Browns at Dolphins (-4, 48.5)

Featured Game | Miami Dolphins vs. Cleveland Browns

Texans at Giants (-6.5, 38.5)

Featured Game | New York Giants vs. Houston Texans

Saints at Steelers (+2.5, 41)

Featured Game | Pittsburgh Steelers vs. New Orleans Saints

Broncos at Titans (-3, 39)

Featured Game | Tennessee Titans vs. Denver Broncos

Colts at Raiders (-6, 42.5)

Featured Game | Las Vegas Raiders vs. Indianapolis Colts

Cowboys at Packers (+5, 43)

Featured Game | Green Bay Packers vs. Dallas Cowboys

Cardinals at Rams (-3, 43.5)

Featured Game | Los Angeles Rams vs. Arizona Cardinals

Chargers at 49ers (-7, 46.5)

Featured Game | San Francisco 49ers vs. Los Angeles Chargers

Monday, November 14th

Commanders at Eagles (-10.5, 44.5)

Featured Game | Philadelphia Eagles vs. Washington Commanders

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