College football picks, schedule: Predictions against the spread, odds for top 25 games Saturday in Week 1

By the time the final whistle blows Saturday night, all but four FBS teams will have played at least one game in the 2022 college football season. In three games, with top 25 opponents battling each other, as well as a few other major matchups across the country, it would be an understatement to say there could be an immediate impact when the first week hits the books.

Two key games of the day saw the power of the Pac-12 head south to take on the top SEC East teams. No. 11 Oregon heads to Atlanta to take on the defending national champion, while No. 3 Georgia looks to beat its former defensive coordinator Dan Lanning, now the Ducks leader. No. 7 Utah, the defending Pac-12 champion and favorite conference champion, heads to the Everglades, Florida hoping one of the toughest environments in college football will help under coach Billy Napier. ) suffered a big setback in Game 1 against the Gators.

Then there’s the Nightcap, the only top-five matchup of previous weeks, as No. 2 Ohio State hosts No. 5 Notre Dame. With three Heisman Trophy contenders and plenty of national championship hype, the Buckeyes will look to delay an Irish campaign aimed at maintaining a high level of play under new coach Marcus Freeman. fighting project.

While winning is important for rankings, we are concerned with how these games will swing from an odds perspective. Be sure to stick with CBS Sports for college football coverage throughout the day, starting with the opening ceremony. Let’s take a look at our expert picks for the best games for Saturday, Week 1.

Caesars Sportsbook Odds | Always East

San Diego State University Arizona

Featured Games | San Diego State Aztecs vs Arizona Wildcats

3:30 PM | CBS,, CBS Sports App The competition features two projects from opposite directions of the competitive spectrum that may meet in the middle of San Diego. The Wildcats made big bets on recruiting and transfers, quickly changing their roster. San Diego State believes new transfer quarterback Braxton Burmeister and a key returner on the defensive end can maintain a top-25 finish. The feisty Wildcats will get enough dynamic play to stay ahead in low-scoring games. Prediction: Arizona (+6) – Sheikhan Jayaraj

Georgia No. 3 vs. Oregon No. 11 (Atlanta)

Featured Games | Georgia Bulldogs vs Oregon Ducks

3:30 PM | ABC, Fubo TV (Free Trial) – The hangover from last year’s win in Indianapolis is long gone. Georgia will show it won’t be complacent and dominate Oregon in what should be a de facto home game. Dan Lanning knows how to attack Georgia’s offensive staff, but stopping it will be a bigger problem. Look for Georgia to come out early on a mission, drag Oregon down in the fourth quarter and rely on the Ducks to get out and cover. Prediction: Georgia (-17) –Barrett Sally

23 Cincinnati, 19 Arkansas

Featured Games | Arkansas Razors vs Cincinnati Bears

ESPN 3:30 p.m., Fubo TV (Free Trial) – It’s an odd situation to me because I don’t think Cincinnati is going to drop that much in 2022, and I don’t think Arkansas is as good as many other places. However, I’m going to have the Razorbacks against the contagion here, because while I expect the Bearcats to be one of the better five-man teams in the country, this is the first game of the season and nine NFL picks have to be replaced, Including their starting quarterback. Arkansas’ experience and home field advantage will ultimately prevail. Prediction: Arkansas -6.5 – Tom Fornelli

Florida No. 7 Utah

Featured Games | Florida Gators vs Utah Utes

7 PM | ESPN, Fubo TV (Free Trial) – As the Gators enter their first year of rebuilding, the Utes are entering a prime year, and the stakes have never been higher for the visitors. While there’s a big hiring gap between the two programs, Utah hasn’t shied away from recruiting stars in the past. In the Rose Bowl, Ohio State hit its limits. The Utes also smashed Oregon twice to undermine the Ducks’ college football playoff case. Take this as a historic victory for the program. Prediction: Utah -3 – Sheikhan Jayaraj

No. 5 Notre Dame at No. 2 Ohio State

Featured Games | Ohio State Buckeyes fight Notre Dame Ireland

7:30 PM | ABC, Fubo TV (Free trial) – In a vacuum or simulation, Ohio State won the game by 20 points, but college football is played by humans, and the stage is too big to imagine a blowout Saturday night. The Buckeyes were under all the pressure and had some nightmarish nights in non-conference games in Columbus, Ohio. In the end, Ohio State is the significantly better team and will win, but the game was fun enough for the Fighting Irish to cover that number. Prediction: Notre Dame +17.5 – Chip Patterson

Which college football picks can you confidently pick in Week 1, and which big favorites will be hard to knock out? Visit SportsLine to see which teams will win and make up the difference — all from a proven computer model that has made nearly $3,600 in profits over the past six-plus seasons — and find out.

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